Laser Assisted Hatching (LAH), is a technique used in in vitro fertilization (IVF) to aid in implanting embryos and achieving pregnancy. This process involves using a laser to create a small opening in the embryo's outer shell before planting it in the uterus. This process loosens the blastocyst within its outer shell, allowing it to implant once deposited into the uterine lining.
There are many reasons why you should choose laser assisted hatching treatment in Nepal. Some of the key reasons for choosing laser assisted hatching treatment in Nepal are as follows:
These are some of the reasons you should choose laser assisted hatching treatment in IVF.
Laser assisted hatching treatment enables a blastocyst to thaw quickly and efficiently without compromising its integrity. Furthermore, it also enhances the implantation and pregnancy rates of eggs. Therefore, it is recommended for the following types of patients.
These are some of the core types of individuals for whom laser assisted hatching treatment in IVF is recommended. Besides the ones we mentioned here, doctors can also recommend this technique depending on your individual circumstances.
One of the key benefits of the laser assisted hatching technique is enhanced implantation and pregnancy rates. Besides this, some other key benefits of LAH are as follows:
Regardless of the medical procedure, there are always some slight risks. Laser assisted hatching in IVF is no exception to this either. Therefore, there are some risks associated with this procedure. The risks of laser assisted hatching treatment are as follows:
Although some of the risks are not worth mentioning, such as the increased cost, they can still be considered a disadvantage of this technique.
The complete laser assisted hatching can be divided into the following steps:
The IVF process is carried out in this process, and the embryos are cultured inside the lab up to the third day.
The embryo is secured on a microscope stage. Then, micromanipulators and lasers are prepared.
Once the devices are set, a 5 to 10-micron opening is drilled in the zona pellucida.
In this stage, the embryo is removed from the setup and planted back into the incubator.
In this phase, the embryo is inspected to confirm that the hole is created and has not damaged the embryo.
The embryo continues developing until day 5 when it reaches the blastocyst stage.
The blastocyst with laser assisted hatching is transferred to the female partner's uterus.
In this final step, a small opening is made via laser, which may promote hatching, implantation, and pregnancy.
The laser assisted hatching success rates range between 30% to 50%
The process involves using a laser to create a small opening (about 5-10 microns wide) in the zona pellucida of the embryo on day 3 after fertilization when it reaches the 6-8 cell stage. This is done using specialized micromanipulation equipment while visualizing the embryo under a microscope. The embryo is then returned to culture until day 5 when it has developed into a blastocyst ready for transfer.
Yes, it does increase the chance of pregnancy to some extent, especially for older women and after frozen embryo transfers.
Some risks of LAH include damage to the embryo if the laser is not precisely targeted, increased chance of monozygotic twins, unnecessary manipulation of the embryo, unknown long-term consequences, and added costs without proven efficacy for all patients.
Laser assisted hatching is typically done on day 3 after fertilization when the embryo is at the 6-8 cell stage. This allows the embryo time to recover and continue developing normally in culture until day 5 when it reaches the blastocyst stage ready for transfer.